Recombinant Human Platelet basic protein(PPBP) (Active)
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產(chǎn)品名稱(chēng): Recombinant Human Platelet basic protein(PPBP) (Active)
產(chǎn)品型號(hào):
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Recombinant Human Platelet basic protein(PPBP) (Active)
Recombinant Human Platelet basic protein(PPBP) (Active)
的詳細(xì)介紹
產(chǎn)品類(lèi)型:Chemokine
產(chǎn)品名稱(chēng):Recombinant Human Platelet basic protein(PPBP) (Active)
uniprot號(hào):
規(guī)格:
￥620
圖像:
基因名稱(chēng):
PPBP
別名:
PBP, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF
種屬:
Homo sapiens (Human)
蛋白描述:
Partial
PubMed ID:
2713489; 1826003; 11468158; 14702039; 15815621; 15489334; 2423119; 15340161; 10877842; 6572368; 12665801; 77677; 8950790; 2783111; 2522778; 7890771; 2406364; 2007144; 9794434; 24275569; 8034022; 7706245
分子量:
7.6 kDa
標(biāo)簽信息:
Tag-Free
來(lái)源:
E.Coli
純度:
>97% as determined by SDS-PAGE and HPLC.
緩沖液:
0.2 μm filtered PBS, pH 7.4 ,lyophilized
內(nèi)毒素:
Less than 1.0 EU/μg as determined by LAL method.
生物活性:
Fully
biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood neutrophils is in a concentration range of 1.0-10.0 ng/ml.
CXCL7_HUMAN
參考文獻(xiàn):
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. {ECO:0000269|PubMed:10877842, ECO:0000269|PubMed:7890771, ECO:0000269|PubMed:8950790, ECO:0000269|PubMed:9794434}.
氨基酸序列:
AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD
表達(dá)區(qū)域:
59-128aa
研究領(lǐng)域:
Immunology
