Recombinant Mouse Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(Il16
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產(chǎn)品名稱: Recombinant Mouse Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(Il16
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Recombinant Mouse Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(Il16) (Active)
Recombinant Mouse Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(Il16
的詳細(xì)介紹
產(chǎn)品類(lèi)型:Interleukin
產(chǎn)品名稱:Recombinant Mouse Pro-interleukin-16 [Cleaved into: Interleukin-16 protein(Il16) (Active)
uniprot號(hào):
規(guī)格:
￥620
圖像:
基因名稱:
Il16
別名:
IL-16, LCF,]
種屬:
Mus musculus (Mouse)
蛋白描述:
Full Length of Mature Protein
PubMed ID:
9637508; 9510557; 10479680; 16141072; 15489334; 21183079
分子量:
12.2 kDa
標(biāo)簽信息:
Tag-Free
來(lái)源:
E.Coli
純度:
>98% as determined by SDS-PAGE and HPLC.
緩沖液:
0.2 μm filtered PBS, pH 7.4 ,lyophilized
內(nèi)毒素:
Less than 1.0 EU/μg as determined by LAL method.
生物活性:
Fully
biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/ml.
IL16_MOUSE
參考文獻(xiàn):
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.; Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.; Isoform 2 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
氨基酸序列:
SAASASAASD ISVESKEATV CTVTLEKTSA GLGFSLEGGK GSLHGDKPLT INRIFKGTEQ GEMVQPGDEI LQLAGTAVQG LTRFEAWNVI KALPDGPVTI VIRRTSLQCK QTTASADS
表達(dá)區(qū)域:
1205-1322aa
研究領(lǐng)域:
Immunology
