Recombinant Mouse Interleukin-6 protein(Il6) (Active)
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產(chǎn)品名稱: Recombinant Mouse Interleukin-6 protein(Il6) (Active)
產(chǎn)品型號:
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Recombinant Mouse Interleukin-6 protein(Il6) (Active)
Recombinant Mouse Interleukin-6 protein(Il6) (Active)
的詳細(xì)介紹
產(chǎn)品類型:Interleukin
產(chǎn)品名稱:Recombinant Mouse Interleukin-6 protein(Il6) (Active)
uniprot號:
規(guī)格:
¥620
圖像:
基因名稱:
Il6
別名:
IL-6, Interleukin HP-1
種屬:
Mus musculus (Mouse)
蛋白描述:
Full Length of Mature Protein
PubMed ID:
2965020; 3263439; 3262872; 2243807; 16141072; 2106569; 2563387; 2948184; 3262059; 2302197; 3264160; 16990136
分子量:
21.7 kDa
標(biāo)簽信息:
Tag-Free
來源:
E.Coli
純度:
>97% as determined by SDS-PAGE and HPLC.
緩沖液:
0.2 μm filtered PBS, pH 7.4 ,lyophilized
內(nèi)毒素:
Less than 1.0 EU/μg as determined by LAL method.
生物活性:
Fully
biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/ml, corresponding to a specific activity of >5x10
7 IU/mg.
Uniprot登錄名:
IL6_MOUSE
參考文獻(xiàn):
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. {ECO:0000269|PubMed:16990136}.
氨基酸序列:
M+FPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
表達(dá)區(qū)域:
25-211aa
研究領(lǐng)域:
Immunology